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Nicotinamide riboside malate is the malate salt form of nicotinamide riboside, a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+) used in research to elevate intracellular NAD+ levels and probe sirtuin-mediated pathways. It is commonly employed in studies of metabolism, aging, and mitochondrial function and is provided as a solid reagent for laboratory research (CAS 2415659-01-5).
Orally bioavailable NAD+ precursor.
Supports increased intracellular NAD+ levels.
Enables sirtuin activation and metabolic pathway studies.
Suitable for research on aging and mitochondrial function.
Supplied as a solid powder for laboratory use.
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. for further information and support please go to the website of the issuing Pharmacopoeia.Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B3). It is available in food products and is utilized for the treatment of pellagra psoriasis nbspschizophrenia andnbsptype I diabetes. It is also known for its anti-inflammatory activity.
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Nicotinamide N-oxide (Nicotinamide 1-oxide 1-oxynicotinamide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD ) in animals Nicotinamide N-oxide is novel potent and selective antagonists of the CXCR2 receptor
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Allopurinol riboside is a drug metabolite of allopurinol reported to have activity against parasites. It is provided for research use as both solid material and concentrated DMSO solutions, with documented solubility, formulation, and storage guidance to support in vitro and in vivo studies.
Drug metabolite with reported antiparasitic activity.
Molecular formula C10H12N4O5; molecular weight 268.23 g/mol.
High purity (≈99%).
Available as solid (1 mg, 5 mg, 10 mg) and as 10 mM solution in DMSO.
Solubility: DMSO 100 mg/mL; stock preparation guidance for 1-10 mM.
Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Formulation guidance provided for achieving ≥2.5 mg/mL in several in vivo vehicles.
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The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator affecting adipose tissue energy expenditure gluconeogenesis and cholesterol biosynthesis Nicotinamide N-Methyltransferase/NNMT Protein Human (His) is the recombinant human-derived Nicotinamide N-Methyltransferase/NNMT protein expressed by E coli with C-His labeled tag
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