Pyridine nucleotides
Crescent Chemical Co Inc NICOTINAMIDE ADENINE DINUCLEOT
Nicotinamide adenine dinucleotide analytical grade Size - 1G Storage Conditions - +2 °C TO +8 °C Catalog Number - 30311.02 CAS 53-84-9
eMolecules Ambeed -Nicotinamide mononucleotide 100mg 525183198 A315149 0 000 1094-61-7 MFCD00038748 334 221 C11H15N2O8P
Ambeed -Nicotinamide mononucleotide 100mg 525183198 A315149 0 000 1094-61-7 MFCD00038748 334 221 C11H15N2O8P
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine100MG
beta Nicotinamide adenine100MG
Apexbio Technology LLC Nicotinamide(Synonyms: Nicotinic acid amide, Vitamin B3 amide, Niacinamide, Pyridine-3-carboxamide, 3-Pyridinecarboxamide), 1g, CAS: 98-92-0.
Nicotinamide (CAS 98-92-0) is a small-molecule inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) an enzyme critical in DNA repair pathways Under pathological conditions such as ischemia or trauma PARP-1 hyperactivation depletes cellular NAD triggering neuronal cell death In vitro studies indicate that transporter-mediated uptake of nicotinamide confers protection against PARP-1-induced astrocyte injury In vivo studies in diabetic rat models demonstrate that nicotinamide administration normalizes hepatic antioxidant enzymes reducing oxidative stress Clinical trials have shown dose-dependent upregulation of frataxin expression following sustained nicotinamide treatment suggesting therapeutic potential in disorders like Friedreich s ataxia
Cayman Chemical 6-MercaptopurIn RIbosIde 100mg
An ionizable cationic lipid (pKa 7.12) intravenous administration of LNPs containing (S)-C12-200 and encapsulating mRNA encoding Cre recombinase increase the percentage of tdTomato hepatocytes endothelial cells and Kupffer cells in the livers of Ai14 mice greater than (R)-C12-200-containing and Cre mRNA-encapsulating LNPs